劉瑞芬 教授 植物-卵菌生物學研究室

◆ 卵菌-植物交互作用

楊雅媛
研究助理

檀佳季
碩士生

吳俊耀
碩士生

成孝軒
碩士生

郭芃妤
碩士生

賴沛宜
碩士生

趙彥愷
碩士生

江秉真
碩士生

陳宜豐
碩士生

《學歷》
美國印地安那大學分子生物學博士
臺灣大學植物病蟲害學系碩士
臺灣大學植物病蟲害學系學士

《經歷》
2004/8–今 臺灣大學植物病理與微生物學系教授
2016/1-2018/12 中華民國真菌學會理事長
2012/3-2013/7 臺灣大學植物醫學碩士學位學程主任
2010/8-2013/7 臺灣大學植物病理與微生物學系主任
2005/8-2008/7 臺灣大學生物技術中心教學組組長
1992/8-2004/7 臺灣大學植物病理與微生物學系副教授
分子生物學
分生技術與原理
植物病原分子檢測與實驗
植物病原交互作用分子機制
Year Article
2021

NbSOBIR1 partitions into plasma membrane microdomains and binds ER-localized NbRLP1

Frontiers in Plant Science

vol.12,page.721548

Li, Yi-Hua, Ke, Tai-Yu, Shih, Wei-Che, Liou, Ruey-Fen*, and Wang, Chao-Wen*

2020

Soil is not a reservoir for Phellinus noxius

Phytopathology

vol.110,no.2,page.362-369

Wu ZC, Chang YY, Lai QJ, Lin HA, Tzean SS, Liou RF, Tsai IJ, Chung CL

2018

Two genes encoding GH10 xylanases are essential for the virulence of the oomycete plant pathogen Phytophthora parasitica

Current Genetics

vol.64,no.4,page.931-943

Lai, M.-W., and Liou, R.-F.*

2017

Comparative and population genomic landscape of Phellinus noxius: A hypervariable fungus causing root rot in trees

Molecular Ecology

vol.26,no.22,page.6301-6316

Chung CL, Lee TJ, Akiba M, Lee HH, Kuo TH, Liu D, Ke HM, Yokoi T, Roa MB, Lu MJ, Chang YY, Ann PJ, Tsai JN, Chen CY, Tzean SS, Ota Y, Hattori T, Sahashi N, Liou RF, Kikuchi T, Tsai IJ.

2017

Phellinus noxius: molecular diversity among isolates from Taiwan and its phylogenetic relationship with other species of Phellinus based on sequences of the ITS region

Botanical Studies

vol.58,no.1,page.9

Tsai JN, Ann PJ, Liou RF, Hsieh WH, Ko WH.

2017

PpMID1 plays a role in the asexual development and virulence of Phytophthora parasitica

Frontiers in Microbiology

vol.8,page.610

Hwu, F. Y., Lai, M. W., and Liou, R. F.*

2016

Development of oligonucleotide microarrays for simultaneous multi-species identification of Phellinus tree-pathogenic fungi

Microbial Biotechnology

vol.9,no.2,page.235-244

Tzean, Y. and Shu, P.-Y. and Liou, R.-F. and Tzean, S.-S.

2015

臺灣臺北及宜蘭地區褐根病菌之遺傳變異分析

植物病理學會刊

vol.24,no.2,page.77-88

黃郁晴 ; 張東柱 ; 鍾嘉綾 ; 劉瑞芬

2015

Tomato SOBIR1/EVR homologs are involved in elicitin perception and plant defense against the oomycete pathogen Phytophthora parasitica

Molecular Plant-Microbe Interactions

vol.28,no.8,page.913-926

Peng, K.-C. and Wang, C.-W. and Wu, C.-H. and Huang, C.-T. and Liou, R.-F.

2015

The genetic structure of Phellinus noxius and dissemination pattern of brown root rot disease in Taiwan

PLoS ONE

vol.10,no.10

Chung, C.-L. and Huang, S.-Y. and Huang, Y.-C. and Tzean, S.-S. and Ann, P.-J. and Tsai, J.-N. and Yang, C.-C. and Lee, H.-H. and Huang, T.-W. and Huang, H.-Y. and Chang, T.-T. and Lee, H.-L. and Liou, R.-F.

2015

A novel elicitor protein from Phytophthora parasitica induces plant basal immunity and systemic acquired resistance

Molecular Plant Pathology

vol.16,no.2,page.123-136

Chang, Y.-H. and Yan, H.-Z. and Liou, R.-F.

2014

應用溫水處理防治愛文檬果採收後果腐病效果評估

植物病理學會刊

vol.23,no.2,page.125-138

倪蕙芳 ; 黃巧雯 ; 劉瑞芬 ; 洪挺軒 ; 楊宏仁

2013

Generation and Analysis of the Expressed Sequence Tags from the Mycelium of Ganoderma lucidum

PLoS ONE

vol.8,no.5

Huang, Y.-H. and Wu, H.-Y. and Wu, K.-M. and Liu, T.-T. and Liou, R.-F. and Tsai, S.-F. and Shiao, M.-S. and Ho, L.-T. and Tzean, S.-S. and Yang, U.-C.

2012

開發檢疫菌Phytophthora ramorum之PCR快速檢測技術

植物病理學會刊

vol.21,no.2,page.53-64

彭可均;安寶貞;林筑蘋;江迪蔚;劉瑞芬

2012

New Botryosphaeriaceae fruit rot of mango in Taiwan: Identification and pathogenicity

Botanical Studies

vol.53,no.4,page.467-478

Ni, H.-F. and Yang, H.-R. and Chen, R.-S. and Liou, R.-F. and Hung, T.-H.

2012

A nested multiplex PCR for species-specific identification and detection of Botryosphaeriaceae species on mango

European Journal of Plant Pathology

vol.133,no.4,page.819-828

Ni, H.-F. and Yang, H.-R. and Chen, R.-S. and Hung, T.-H. and Liou, R.-F.

2010

First report of fruit rot disease of mango caused by Botryosphaeria dothidea and Neofusicoccum mangiferae in Taiwan

Plant Disease

vol.94,no.1

Ni, H.F. and Liou, R.F. and Hung, T.H. and Chen, R.S. and Yang, H.R.

2009

First report of a fruit rot disease of avocado caused by neofusicoccum mangiferae

Plant Disease

vol.93,no.7

Ni, H.F. and Liou, R.F. and Hung, T.H. and Chen, R.S. and Yang, H.R.

2008

Functional characterization of a gene family encoding polygalacturonases in Phytophthora parasitica

Molecular Plant-Microbe Interactions

vol.21,no.4,page.480-489

Wu, C.-H. and Yan, H.-Z. and Liu, L.-F. and Liou, R.-F.

2006

Selection of internal control genes for real-time quantitative RT-PCR assays in the oomycete plant pathogen Phytophthora parasitica

Fungal Genetics and Biology

vol.43,no.6,page.430-438

Yan, H.-Z. and Liou, R.-F.

2006

Detection of orchid Phytophthora disease by nested PCR

Botanical Studies

vol.47,no.4,page.379-387

Tsai, H.-L. and Huang, L.-C. and Ann, P.-J. and Liou, R.-F.

2005

Cloning and analysis of pppg1, an inducible endopolygalacturonase gene from the oomycete plant pathogen Phytophthora parasitica

Fungal Genetics and Biology

vol.42,no.4,page.339-350

Yan, H.-Z. and Liou, R.-F.

2004

引起紅龍果斑駁病徵之Cactus Virus X的鑑定與免疫檢測

植物病理學會刊

vol.13,no.1,page.27-34

劉命如 ; 洪建龍 ; 劉瑞芬

2004

Complete nucleotide sequence and genome organization of a Cactus virus X strain from Hylocereus undatus (Cactaceae)

Archives of Virology

vol.149,no.5,page.1037-1043

Liou, M.R. and Chen, Y.R. and Liou, R.F.

2003

鶯歌桃果實疫病

植物病理學會刊

vol.12,no.3,page.181-190

安寶貞 ; 蔡志濃 ; 王姻婷 ; 石信德 ; 黃振文 ; 劉瑞芬

2003

Molecular evidence that aphid-transmitted Alpinia mosaic virus is a tentative member of the genus Macluravirus

Archives of Virology

vol.148,no.6,page.1211-1218

Liou, R.F. and Yan, H.Z. and Hong, J.L.

2002

The period gene of the German cockroach and its novel linking power between vertebrate and invertebrate

Chronobiology International

vol.19,no.6,page.1023-1040

Lin, G.G.-H. and Liou, R.-F. and Lee, H.-J.

2002

Rapid Detection of Phytophthora infestans by PCR

植物病理學會刊

vol.11,no.1,page.25-32

簡明宏 ; 黃麗君 ; 安寶貞 ; 劉瑞芬

2002

Analysis of Phytophthora parasitica by retrotransposon-derived DNA fingerprinting

Botanical Bulletin of Academia Sinica

vol.43,no.1,page.21-29

Liou, R.-F. and Lee, J.-T. and Lee, H.-C. and Ann, P.-J.

2001

疫病菌誘導蛋白elicitins之研究現況

植物病理學會刊

vol.10,no.3,page.97-104

劉瑞芬

1999

First Report of Phytophthora blight of White Arum Lily caused by Phytophthora meadii

Plant Pathology Bulletin

vol.8,page.37-40

Ruey-Fen Liou , Jent-Turn Lee , and Pao-Jen Ann

1993

Snake venom cardiotoxin can rapidly induce actin polymerization in intact platelets

Biochemical Journal

vol.290,no.2,page.591-594

Liou, R.-F. and Chang, W.-C. and Chu, S.-T. and Chen, Y.-H.

1993

Conversion of a trans-spliced C.elegans gene into a conventional gene by introduction of a splice donor site

EMBO Journal

vol.12,no.3,page.1249-1255

Conrad, R. and Liou, R.F. and Blumenthal, T.

1990

trans-Spliced Caenorhabditis elegans mRNAs retain trimethylguanosine caps

Molecular and Cellular Biology

vol.10,no.4,page.1764-1768

Liou, R.-F. and Blumenthal, T.

1987

Interaction of snake venom cardiotoxin (a membrane-disruptive polypeptide) with human erythrocytes

Molecular and Cellular Biochemistry

vol.73,no.1,page.69-76

Chen, Y.-H. and Liou, R.-F. and Hu, C. and Juan, C.-C. and Yang, J.T.

Year Article
1995

Complete nucleotide sequence of beauveria bassiana 5.8s rRNA coding gene and flanking internal transcribed spacers

Mitochondrial DNA

vol.5,no.6,page.381-383

Shih, H.L. and Lin, C.P. and Liou, R.F. and Tzean, S.S.

研究室簡介

◆ 疫病菌與寄主植物之交互作用

疫病菌屬 (Phytophthora) 包含100多種疫病菌,其中許多為植物重要病原菌,例如在馬鈴薯與番茄引發晚疫病的 Phytophthora infestans、在大豆引發疫病的 Phytophthora sojae、寄主範圍至為廣泛的 Phytophthora parasitica (= P. nicotianae) 與Phytophthora capsici 等,相關研究一直備受重視。近年來,不論研究病原菌基因體學或探討病原菌與寄主植物的交互作用,疫病菌也一直是眾所矚目的焦點。本研究室主要研究 P. parasitica 與番茄、菸草等茄科植物的交互作用,除了探討植物對疫病菌基礎防禦反應所涉機制,也致力於自 P. parasitica 發現novel elicitors/ apoplastic effectors,並分析其功能與特性。此外,我們也建立重要疫病菌的分子檢測技術及P. infestans 基因分型技術,期能應用於快速檢測,以助鑑別疫病菌種類及瞭解晚疫病菌族群在田間的存在情形。另一方面,亦著手開發疫病菌防治技術,希望有助於防治病害。​

圖:晚疫病菌在馬鈴薯葉片所造成之病斑