Shen, Wei-Chiang Professor Fungal Physiology and Molecular Biology Laboratory

Molecular dissection of signal transduction pathways regulating mating, filamentous growth, and virulence in human pathogenic fungus, Cryptococcus neoformans
Study of the molecular mechanisms regulating the pathogenesis in plant pathogenic fungi
Characterization of the biosynthetic pathway of bioactive polysaccharides in Ganoderma lucidum
Development of transformation and expression systems in Ganoderma lucidum
Development of the novel control technique for guava Myxosporium wilt

Sabnam Rai
Ph.D. Student

Shan-Syuan Fang
M.S. Student

r05633020@ntu.edu.tw

賴軒
M.S. Student

劉廣宏
Ph.D. Student

Jauhar Syauqi
M.S. Student

施媞佳
M.S. Student

2011-Present Professor, Dept. of Plant Pathology and Microbiology, National Taiwan University
2005-2011 Associate Professor, Dept. of Plant Pathology and Microbiology, National Taiwan University
2000-2005 Assistant Professor, Dept. of Plant Pathology and Microbiology, National Taiwan University
1999-2000 Postdoctoral research fellow, Dept. of Genetics, Medical Center Duke University North Carolina, USA
1993-1999 Graduate Research Assistant, Dept. of Plant Pathology and Microbiology, Texas A&M University College Station, Texas, USA
1991-1993 Research Assistant Institute of Molecular Biology, Academia Sinica, Nankang, Taipei, Taiwan
1989-1991 Graduate Research Assistant, Dept. of Plant Pathology and Entomology National Taiwan University, Taiwan

PhD. Plant Pathology and Microbiology, Texas A&M University, USA
◆ 微生物生理學
◆ 微生物研究法
◆ 進階 微生物學
◆ 微生物學實驗
◆ 醫用真菌學特論
◆ 真菌生理學
◆ 現代分子真菌學
◆ 植物分子檢測與實驗 (合授)
◆ 生物技術核心實驗 (合授)
◆ 植物病理研究法與實驗 (合授)
◆ 人畜共通傳染病概論 (合授)
Year Article
2015

Pilot study of mold in homes of asthmatic children in Taipei, Taiwan, using the Environmental Relative Moldiness Index

Aerobiologia

vol.31,no.2,page.213-218

Chen, C.-H. and Chao, H.J. and Shen, W.-C. and Chen, B.-Y. and Lin, K.-T. and Guo, Y.L. and Vesper, S.

2013

病例報告:Prototheca wickerhamii引起犬皮膚型原壁藻症一例

臺灣獸醫學雜誌

2012

Autofluorescence approaches to observation of mycorrhizal colonization in five orchids

Advanced Science Letters

vol.13,page.400-405

Lee, M.-C. and Hsu, J.-H. and Cheng, S.-F. and Chang, D.C.N. and Shen, W.-C. and Chang, Y.-S.

2011

Mating differentiation in Cryptococcus neoformans is negatively regulated by the Crk1 protein kinase

Fungal Genetics and Biology

vol.48,no.3,page.225-240

Liu, K.-H. and Shen, W.-C.

2011

Fast preparation of fungal DNA for PCR screening

Journal of Microbiological Methods

vol.85,no.2,page.170-172

Liu, K.-H. and Yeh, Y.-L. and Shen, W.-C.

2011

Cryptococcus neoformans mediator protein Ssn8 negatively regulates diverse physiological processes and is required for virulence

PLoS ONE

vol.6,no.4

Wang, L.-I. and Lin, Y.-S. and Liu, K.-H. and Jong, A.Y. and Shen, W.-C.

2011

Arsenite-oxidizing and arsenate-reducing bacteria associated with arsenic-rich groundwater in Taiwan

Journal of Contaminant Hydrology

vol.123,no.1-2,page.20-29

Liao, V.H.-C. and Chu, Y.-J. and Su, Y.-C. and Hsiao, S.-Y. and Wei, C.-C. and Liu, C.-W. and Liao, C.-M. and Shen, W.-C. and Chang, F.-J.

2009

Phylogenetic study of two truffles, Tuber formosanum and Tuber furfuraceum, identified from Taiwan

FEMS Microbiology Letters

vol.294,no.2,page.157-171

Huang, J.-Y. and Hu, H.-T. and Shen, W.-C.

2009

Photo-enhancement of Cr(VI) reduction by fungal biomass of Neurospora crassa

Applied Catalysis B: Environmental

vol.92,no.3-4,page.294-300

Lin, Y.C. and Wang, S.L. and Shen, W.C. and Huang, P.M. and Chiang, P.N. and Liu, J.C. and Chen, C.C. and Tzou, Y.M.

2009

A screening for suppressor mutants reveals components involved in the blue light-inhibited sexual filamentation in Cryptococcus neoformans

Fungal Genetics and Biology

vol.46,no.1,page.42-54

Yeh, Y.-L. and Lin, Y.-S. and Su, B.-J. and Shen, W.-C.

2005

Classification of the guava wilt fungus Myxosparium psidii, the palm pathogen Gliocladium vermoesenii and the persimmon wilt fungus Acremonium diospyri in Nalanthamala

Mycologia

vol.97,no.2,page.375-395

Schroers, H.-J. and Geldenhuis, M.M. and Wingfield, M.J. and Schoeman, M.H. and Yen, Y.-F. and Shen, W.-C. and Wingfield, B.D.

2005

Blue light negatively regulates the sexual filamentation via the Cwc1 and Cwc2 proteins in Cryptococcus neoformans

Molecular Microbiology

vol.56,no.2,page.480-491

Lu, Y.-K. and Sun, K.-H. and Shen, W.-C.

2005

A homolog of Ste6, the a-factor transporter in Saccharomyces cerevisiae, is required for mating but not for monokaryotic fruiting in Cryptococcus neoformans

Eukaryotic Cell

vol.4,no.1,page.147-155

Hsueh, Y.-P. and Shen, W.-C.

2002

Pheromones stimulate mating and differentiation via paracrine and autocrine signaling in Cryptococcus neoformans

Eukaryotic Cell

vol.1,no.3,page.366-377

Shen, W.-C. and Davidson, R.C. and Cox, G.M. and Heitman, J.

2000

Signal transduction cascades regulating fungal development and virulence

Microbiology and Molecular Biology Reviews

vol.64,no.4,page.746-785

Lengeler, K.B. and Davidson, R.C. and D{'

1999

Isolation of pheromone precursor genes of Magnaporthe grisea

Fungal Genetics and Biology

vol.27,no.2-3,page.253-263

Shen, W.-C. and Bobrowicz, P. and Ebbole, D.J.

1998

The neurospora rca-1 gene complements an Aspergillus flbD sporulation mutant but has no identifiable role in neurospora sporulation

Genetics

vol.148,no.3,page.1031-1041

Shen, W.-C. and Wieser, J. and Adams, T.H. and Ebbole, D.J.

1997

Cross-pathway and pathway-specific control of amino acid biosynthesis in magnaporthe grisea

Fungal Genetics and Biology

vol.21,no.1,page.40-49

Shen, W.-C. and Ebbole, D.J.

1992

Differential expression of Hz-1 baculovirus genes during productive and persistent viral infections

Journal of Virology

vol.66,no.3,page.1442-1448

Chao, Y.-C. and Wood, H.A. and Chang, C.-Y. and Lee, H.-J. and Shen, W.-C. and Lee, H.-T.

About Us

研究方向

◆ 人體病原真菌隱球菌致病性、生殖生理及發生分子調控機制之研究。
◆ 臺灣水稻稻熱病菌族群特性之研究。
◆ 植物病原真菌致病性分子調控機制之研究。
◆ 藥用真菌功能基因體之研究。